HUR-MEDIATED NUCLEOCYTOPLASMIC TRANSLOCATION OF HOTAIR RELIEVES ITS INHIBITION OF OSTEOGENIC DIFFERENTIATION AND PROMOTES BONE FORMATION

Abstract Bone marrow mesenchymal stem cell (BMSC) osteogenic differentiation and osteoblast function play critical roles in bone formation, which is a highly regulated process.Long noncoding RNAs (lncRNAs) perform diverse functions in a variety of biological processes, including BMSC osteogenic differentiation.Although several studies have reported

Progression-free survival (PFS) of patients with lower-risk myelodysplastic syndromes (MDS) treated with red blood cell transfusions is usually reduced, but it is unclear whether transfusion dose density is an independent prognostic factor.The European MDS Registry collects prospective data at 6-monthly intervals Induction Range from newly diagnose